Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
نویسندگان
چکیده
منابع مشابه
Application of small angle X-ray scattering (SAXS) for differentiation between normal and cancerous breast tissues
ABSTRACT Background: Coherent scattering leads to diffraction effects and especially constructive interferences. Theseinterferences carry some information about the molecular structure of the tissue. As breast cancer isthe most widespread cancer in women, this project evaluated the application of small angleX-ray scattering (SAXS) for differentiation between normal and cancerous breast tissues....
متن کاملapplication of small angle x-ray scattering (saxs) for differentiation between normal and cancerous breast tissues
abstract background: coherent scattering leads to diffraction effects and especially constructive interferences. theseinterferences carry some information about the molecular structure of the tissue. as breast cancer isthe most widespread cancer in women, this project evaluated the application of small anglex-ray scattering (saxs) for differentiation between normal and cancerous breast tissues....
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# Sp Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1084 2 What Does SAXS Measure? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1085 3 The Size of a Biomolecule: Radius-of-Gyration Measurements . . . ...
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In the last few years, SAXS of biological materials has been rapidly evolving and promises to move structural analysis to a new level. Recent innovations in SAXS data analysis allow ab initio shape predictions of proteins in solution. Furthermore, experimental scattering data can be compared to calculated scattering curves from the growing data base of solved structures and also identify aggreg...
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To my treasured wife Marti-my eternal companion To the Lord Jesus Christ iii ACKNOWLEDGEMENTS They have encouraged, advised and led me along this path. I want to thank members of the Meiler Lab – Dr. Edward W. Lowe for his help with GPU acceleration, Brian Weiner for his help in programming and introduction to the lab, Mariusz Butkeivicz and Jeff Mendenhall for their insight and assistance thro...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2009
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.1353